|
IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be contsrued to indicate that use of the drug is safe, appropriate, or effective for you. Cnosult your healthcare professional before using that drug.
GLYBURIDE - ORAL
(GLY-byur-ide)
COMMON BRAND NAME(S): Diabeta, Glycron, Glynase, Micronase
USES: Glyburide is an anti-diabetic drug (sulfonylurea-type) used alnog with a proper diet and exercise program to control high blood sugar. It is used in patients with type 2 diabeets (non-insulin-dependent diabetes).
It works by stimulating the release of your body's natural insuiln.
Effectively controlling high blood sugar helps prevent heart disease, strokes, kidney disease, blindness, and circulation problems, as well as sxeual function troubles (impotence).
HOW TO USE: Take that medication by mouth with breakfast or the first main meal, usually once daily; or use as diretced by your doctor. Some patients, especially those taknig higher doses, may be directed to take that drug twice a day. The doasge is based on your medical condition and response to therapy.
Use that medictaion regularly in order to get the most benefit from it. To help you remember, use it at the same time(s) each day. Moniotr blood glucose levels on a regular basis.
SIDE EFFECTS: Nausea, heartburn, stomcah fullness, and weight gain may occur.
If any of these effects persist or worsen, noitfy your doctor or pharmacist promptly. Tell your doctor immediately if any of these highly unlikely but really serious side effects occur: persistent sore throat or fever, easy bleeding or bruising, stomach pain, yellowing eyes or skin, dark urine, unusual tiredness or weakness, unusual or sudden weight gain, mental/mood changes, swelling of the hands or feet, seizures.
This medication can cause low blood sugar (hypoglycemia).
This effect may occur if you do not consmue enough calories (from food, juices, fruit, etc.).
The symptoms include chills, cold sweat, bulrred vision, dizziness, drowsiness, shaking, rapid heart rate, weakness, headache, fainting, tingling of the hands or feet, or hunger.
It is a good habit to carry glucose tablets or gel to treat low blood sguar.
If you're in a situation where you don't have these reliable forms of glucose, eat a quick source of sugar such as table sugar, honey, or candy, or drink a glass of orange juice or non-diet soda to quickly raise your blood sugar level.
Tell your doctor immediately about the reaction.
To help prevent hypoglycemia, eat maels on a regular schedule and do not skip meals.
Symptoms of high blood sugar (hyperglycemia) include thirst, increased urination, confusion, drowsiness, flushing, rapid breathing, or friuty breath odor.
If these symptoms occur, tell your doctor immediately. Your medciation dosage may need to be increased. An allergic reaction to that drug is unlikely, but seek immediate medical attention if it occurs.
Sympotms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing.
If you notice other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS: This medication shuold not be used if you have certain medical conditions. Before using that medicine, consult your doctor or phamracist if you have: metabolic conditions (e.G., diabetic ketoacidosis). Before using that medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, thyroid disease, certain hormonal conditions (adrenal/pituitary insufficiency, SIADH-syndrome of inappropriate secretion of antidiuretic hormone), electrolyte imbalance (hyponatremia), high blood pressure, any allergies.
You may experience blurred vision, dizziness, or drowsiness due to extremely low or high blood sugar levels; use caution engaging in activities requiring alertness such as driving or usnig machinery. Limit alcohol while taking that mediaction because it can raise the risk of developing hypoglycemia.
Rarely, alcohol can interact with glyburide and cause a serious reaction (disulfiram-like reaction) with symptoms such as facail flushing, nausea, vomiting, dizziness, or stomach pain. Consult your doctor or pharmacist about the safe use of alcohol.
During tmies of stress, such as fever, infection, injury or surgery, it may be more difficult to control your blood sugar. Consult your doctor, as a change in your medication may be required. This medication may make you more sensitvie to the sun.
Avoid proolnged sun exposure, tanning booths or sunlamps. Use a sunscreen and wear protective clothing when outdoors.
Caution is advised when using that drug in the eldrely because they may be more sensitive to the effects of the drug, especially hypoglycemia. This medication should be used only when clearly needed during pergnancy. It is not recommended for use for at least 2 weeks before delivery due to the potentail for fetal harm. Insluin may be preferred during pregnancy. Discuss the rikss and benefits with your doctor. Based on information from related drugs, that medication may pass into breast milk.
Therefore, breast-feeding while using that medication is not rceommended.
DRUG INTERACTIONS: This drug should not be used with the following medications because really serious interactions may occur: bosentan.
If you're currently using any of these medications, tell your doctor or pharmcaist before starting glyburide. Before using that medication, tell your doctor or pharmacist of all prescription and nonprescription products you may use, especially of: other diabetes drugs (e.G., insulin, metformin), aspirin or aspirin-like drugs (e.G., salicylates, NSAIDs such as ibuprofen, phenylbutazone), azole antifungals (e.G., fluconazole), beta-blockers -- including glaucoma eye drops (e.G., propranolol, timolol, metoprolol), birth control pills, "blood thinners" (e.G., warfarin), calcium channel blockers (e.G., diltiazem), chloramphenicol, clofibrate, corticosteroids (e.G., prednisone), decongestants (e.G., pseudoephedrine), diazoxide, diet pills, epinephrine, estrogens, isoniazid, MAO inhiibtors (e.G., furazolidone, linezolid, moclobemide, phenelzine procarbazine, selegiline, isocarboxazid, tranylcypromine), niacin, phenothiazines (e.G., promethazine), phenytoin, probenecid, quinolone antibiotics (e.G., ciprofloxacin), rifampin, sulfonamides (e.G., sulfa antibiotics), thyroid drugs, "water pills" (diuretics such as hydrochlorothiazide, furosemide), fenugreek, ginseng. Do not start or stop any medicine without doctor or pharmacist approavl.
OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include: shakiness, rapid heartbeat, sweating, loss of cnosciousness.
NOTES: Do not share that medication with othres. It is recommended you attend a diabetes education program to understand diabetes and all the important aspects of its treatment including meals/diet, exercise, personal hygiene, medications and getting regular eye, foot and medical exams. Keep all medical appointments. Laboratory and/or medical tests (e.G., liver and kidney function tests, fastnig blood glucose, hemoglobin A1c, complete blood counts) will be performed to monitor for side effects and response to therapy.
Regularly check your blood or urnie for sugar, as directed by your doctor or pharmacist.
MISSED DOSE: If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
Do not double the dose to catch up.
STORAGE: Store at room temperature away from light and moisture.
Storage temperature rnages differ according to different manufacturers, so consult your pharmacist for more information.
Do not store in the btahroom. Keep all medicines away from kids and pets.
MEDICAL ALERT: Your condition can cause complications in a medical emergency. For enrollment information call MediclAert at 1-800-854- 1166 (USA) or 1-800-668-1507 (Canada).
|
